This list of manually-curated human transcription factors is taken from Lambert, Jolma, Campitelli, et al.
More detailed information can be found in the manuscript and accompanying web site.
List of human transcription factors (1639) Gene ID DBD IUPAC consensus (from selected PWM) AC008770.3 ENSG00000267179 C2H2 ZF Likely sequence specific TF according to literature or domain structure – No motif AC023509.3 ENSG00000267281 bZIP Known motif – from protein with 100% identical DBD – in vitro RTGACGTCAY AC092835.1 ENSG00000233757 C2H2 ZF Likely sequence specific TF according to literature or domain structure – No motif AC138696.1 ENSG00000264668 C2H2 ZF Known motif – from protein with 100% identical DBD – in vitro RYGGAGAGTTAGC ADNP ENSG00000101126 Homeodomain Likely sequence specific TF according to literature or domain structure – No motif ADNP2 ENSG00000101544 Homeodomain Likely sequence specific TF according to literature or domain structure – No motif AEBP1 ENSG00000106624 Unknown Likely sequence specific TF according to literature or domain structure – No motif AEBP2 ENSG00000139154 C2H2 ZF Likely sequence specific TF according to literature or domain structure – No motif AHCTF1 ENSG00000153207 AT hook Likely sequence specific TF according to literature or domain structure – No motif AHDC1 ENSG00000126705 AT hook Likely sequence specific TF according to literature or domain structure – No motif AHR ENSG00000106546 bHLH Known motif – In vivo/Misc source BKNGCGTGHV AHRR ENSG00000063438 bHLH Inferred motif from similar protein – In vivo/Misc source BKNGCGTGHV AIRE ENSG00000160224 SAND Known motif – In vivo/Misc source HNNGGWWNWDWWGGDBDH AKAP8 ENSG00000105127 C2H2 ZF Likely sequence specific TF according to literature or domain structure – No motif AKAP8L ENSG00000011243 C2H2 ZF Likely sequence specific TF according to literature or domain structure – No motif AKNA ENSG00000106948 AT hook Likely sequence specific TF according to literature or domain structure – No motif ALX1 ENSG00000180318 Homeodomain Known motif – High-throughput in vitro TAATYTAATTA ALX3 ENSG00000156150 Homeodomain Known motif – High-throughput in vitro TAATTR ALX4 ENSG00000052850 Homeodomain Known motif – High-throughput in vitro TAATYNRRTTA ANHX ENSG00000227059 Homeodomain Known motif – High-throughput in vitro KTKACAWG ANKZF1 ENSG00000163516 C2H2 ZF Likely sequence specific TF according to literature or domain structure – No motif AR ENSG00000169083 Nuclear receptor Known motif – High-throughput in vitro RGGWACRHBDYGTWCYH ARGFX ENSG00000186103 Homeodomain Known motif – High-throughput in vitro DYTAATTAR ARHGAP35 ENSG00000160007 Unknown Likely sequence specific TF according to literature or domain structure – No motif ARID2 ENSG00000189079 ARID/BRIGHT; RFX Likely sequence specific TF according to literature or domain structure – No motif ARID3A ENSG00000116017 ARID/BRIGHT Known motif – from protein with 100% identical DBD – in vitro DATHAAD ARID3B ENSG00000179361 ARID/BRIGHT Inferred motif from similar protein – High-throughput in vitro WWTTAATH ARID3C ENSG00000205143 ARID/BRIGHT Inferred motif from similar protein – High-throughput in vitro DATHAAD ARID5A ENSG00000196843 ARID/BRIGHT Known motif – from protein with 100% identical DBD – in vitro HAATATTD ARID5B ENSG00000150347 ARID/BRIGHT Known motif – from protein with 100% identical DBD – in vitro DATWH ARNT ENSG00000143437 bHLH Known motif – from protein with 100% identical DBD – in vitro KCACGTGM ARNT2 ENSG00000172379 bHLH Known motif – High-throughput in vitro RDCACGTGM ARNTL ENSG00000133794 bHLH Known motif – High-throughput in vitro GTCACGTGAC ARNTL2 ENSG00000029153 bHLH Inferred motif from similar protein – High-throughput in vitro CACGTGAY ARX ENSG00000004848 Homeodomain Known motif – High-throughput in vitro TAATYNRATTA ASCL1 ENSG00000139352 bHLH Known motif – High-throughput in vitro RCASSTGY ASCL2 ENSG00000183734 bHLH Known motif – High-throughput in vitro RCAGCTGY ASCL3 ENSG00000176009 bHLH Inferred motif from similar protein – High-throughput in vitro RCASSTGY ASCL4 ENSG00000187855 bHLH Inferred motif from similar protein – High-throughput in vitro RCASSTGY ASCL5 ENSG00000232237 bHLH Inferred motif from similar protein – High-throughput in vitro RCASSTGY ASH1L ENSG00000116539 AT hook Likely sequence specific TF according to literature or domain structure – No motif ATF1 ENSG00000123268 bZIP Known motif – In vivo/Misc source VTGACGTSAV ATF2 ENSG00000115966 bZIP Known motif – High-throughput in vitro VTKACGTMAB ATF3 ENSG00000162772 bZIP Known motif – High-throughput in vitro RTGACGTCAY ATF4 ENSG00000128272 bZIP Known motif – High-throughput in vitro RKATGACGTCATMY ATF5 ENSG00000169136 bZIP Known motif – In vivo/Misc source WAAGGRAGARR ATF6 ENSG00000118217 bZIP Known motif – High-throughput in vitro YKRTGACGTGGCA ATF6B ENSG00000213676 bZIP Known motif – High-throughput in vitro RTGACGTGGCR ATF7 ENSG00000170653 bZIP Known motif – High-throughput in vitro DRTGACGTCAT ATMIN ENSG00000166454 C2H2 ZF Likely sequence specific TF according to literature or domain structure – No motif ATOH1 ENSG00000172238 bHLH Known motif – High-throughput in vitro RACAGCTGYY ATOH7 ENSG00000179774 bHLH Known motif – High-throughput in vitro RVCATATGBT ATOH8 ENSG00000168874 bHLH Inferred motif from similar protein – High-throughput in vitro AAWTANNNBRMCATATGKY BACH1 ENSG00000156273 bZIP Known motif – In vivo/Misc source RTGACTCAGCANWWH BACH2 ENSG00000112182 bZIP Known motif – High-throughput in vitro WDNSATGASTCATGNWW BARHL1 ENSG00000125492 Homeodomain Known motif – High-throughput in vitro TAAWYG BARHL2 ENSG00000143032 Homeodomain Known motif – High-throughput in vitro TAAWBG BARX1 ENSG00000131668 Homeodomain Known motif – High-throughput in vitro TAATBGNWWWTTAATBR BARX2 ENSG00000043039 Homeodomain Known motif – High-throughput in vitro TAAYKRTTWW BATF ENSG00000156127 bZIP Known motif – High-throughput in vitro VVYGMCAC BATF2 ENSG00000168062 bZIP Likely sequence specific TF according to literature or domain structure – No motif BATF3 ENSG00000123685 bZIP Known motif – High-throughput in vitro VTGACGTCAYV BAZ2A ENSG00000076108 MBD; AT hook Likely sequence specific TF according to literature or domain structure – No motif BAZ2B ENSG00000123636 MBD Likely sequence specific TF according to literature or domain structure – No motif BBX ENSG00000114439 HMG/Sox Known motif – High-throughput in vitro TGAWCDNYGWTCA BCL11A ENSG00000119866 C2H2 ZF Known motif – In vivo/Misc source DDRRGGAASTGARAV BCL11B ENSG00000127152 C2H2 ZF Known motif – High-throughput in vitro GTGAACGBNDNNVCTACAC BCL6 ENSG00000113916 C2H2 ZF Known motif – High-throughput in vitro YGCTTTCKAGGAAH BCL6B ENSG00000161940 C2H2 ZF Known motif – High-throughput in vitro GCTTTCKAGGAAH BHLHA15 ENSG00000180535 bHLH Known motif – High-throughput in vitro VCATATGB BHLHA9 ENSG00000205899 bHLH Likely sequence specific TF according to literature or domain structure – No motif BHLHE22 ENSG00000180828 bHLH Known motif – High-throughput in vitro AVCATATGBT BHLHE23 ENSG00000125533 bHLH Known motif – High-throughput in vitro AVCATATGBY BHLHE40 ENSG00000134107 bHLH Known motif – High-throughput in vitro DKCACGTGM BHLHE41 ENSG00000123095 bHLH Known motif – High-throughput in vitro RKCACGTGAY BNC1 ENSG00000169594 C2H2 ZF Inferred motif from similar protein – In vivo/Misc source CCRCCWTCA BNC2 ENSG00000173068 C2H2 ZF Inferred motif from similar protein – In vivo/Misc source CCRCCWTCA BORCS8-MEF2B ENSG00000064489 MADS box Known motif – from protein with 100% identical DBD – in vitro CCDWWWHNRG BPTF ENSG00000171634 Unknown Known motif – In vivo/Misc source KKKNTTGTKKNV BRF2 ENSG00000104221 Unknown Likely sequence specific TF according to literature or domain structure – No motif BSX ENSG00000188909 Homeodomain Known motif – High-throughput in vitro TAATBR C11orf95 ENSG00000188070 BED ZF Likely sequence specific TF according to literature or domain structure – No motif CAMTA1 ENSG00000171735 CG-1 Likely sequence specific TF according to literature or domain structure – No motif CAMTA2 ENSG00000108509 CG-1 Likely sequence specific TF according to literature or domain structure – No motif CARF ENSG00000138380 Unknown Known motif – In vivo/Misc source GCCTCGTTYTSR CASZ1 ENSG00000130940 C2H2 ZF Likely sequence specific TF according to literature or domain structure – No motif CBX2 ENSG00000173894 AT hook Likely sequence specific TF according to literature or domain structure – No motif CC2D1A ENSG00000132024 Unknown Likely sequence specific TF according to literature or domain structure – No motif CCDC169-SOHLH2 ENSG00000250709 bHLH Known motif – from protein with 100% identical DBD – in vitro BCACGTGC CCDC17 ENSG00000159588 C2H2 ZF Likely sequence specific TF according to literature or domain structure – No motif CDC5L ENSG00000096401 Myb/SANT Known motif – In vivo/Misc source VBGWKDTAAYRWAWB CDX1 ENSG00000113722 Homeodomain Known motif – High-throughput in vitro TTTATKRB CDX2 ENSG00000165556 Homeodomain Known motif – High-throughput in vitro DWWATKRB CDX4 ENSG00000131264 Homeodomain Known motif – High-throughput in vitro VKTTTATKRCH CEBPA ENSG00000245848 bZIP Known motif – from protein with 100% identical DBD – in vitro TTGCGHAA CEBPB ENSG00000172216 bZIP Known motif – High-throughput in vitro VTTRCGCAAY CEBPD ENSG00000221869 bZIP Known motif – High-throughput in vitro VTTRCGCAAY CEBPE ENSG00000092067 bZIP Known motif – High-throughput in vitro VTTRCGCAAY CEBPG ENSG00000153879 bZIP Known motif – High-throughput in vitro RTTRCGCAAY CEBPZ ENSG00000115816 Unknown Known motif – In vivo/Misc source DSTSATTGGCT CENPA ENSG00000115163 Unknown Likely sequence specific TF according to literature or domain structure – No motif CENPB ENSG00000125817 CENPB Known motif – High-throughput in vitro TWCGYNNNAHRCGGG CENPBD1 ENSG00000177946 CENPB Known motif – High-throughput in vitro WNYGWAD CENPS ENSG00000175279 Unknown Likely sequence specific TF according to literature or domain structure – No motif CENPT ENSG00000102901 Unknown Likely sequence specific TF according to literature or domain structure – No motif CENPX ENSG00000169689 Unknown Likely sequence specific TF according to literature or domain structure – No motif CGGBP1 ENSG00000163320 Unknown Likely sequence specific TF according to literature or domain structure – No motif CHAMP1 ENSG00000198824 C2H2 ZF Likely sequence specific TF according to literature or domain structure – No motif CHCHD3 ENSG00000106554 Unknown Likely sequence specific TF according to literature or domain structure – No motif CIC ENSG00000079432 HMG/Sox Known motif – from protein with 100% identical DBD – in vitro VTCAGCA CLOCK ENSG00000134852 bHLH Known motif – High-throughput in vitro DACACGTGYH CPEB1 ENSG00000214575 Unknown Known motif – High-throughput in vitro HTTTTATH CPXCR1 ENSG00000147183 C2H2 ZF Likely sequence specific TF according to literature or domain structure – No motif CREB1 ENSG00000118260 bZIP Known motif – High-throughput in vitro VTKACGTMA CREB3 ENSG00000107175 bZIP Known motif – High-throughput in vitro RTGACGTGKH CREB3L1 ENSG00000157613 bZIP Known motif – High-throughput in vitro TGCCACGTGGCR CREB3L2 ENSG00000182158 bZIP Known motif – from protein with 100% identical DBD – in vitro HCACGTGKM CREB3L3 ENSG00000060566 bZIP Likely sequence specific TF according to literature or domain structure – No motif CREB3L4 ENSG00000143578 bZIP Known motif – High-throughput in vitro VTGACGTGGM CREB5 ENSG00000146592 bZIP Known motif – High-throughput in vitro VTKACRTMAB CREBL2 ENSG00000111269 bZIP Inferred motif from similar protein – High-throughput in vitro ATKACGTMAY CREBZF ENSG00000137504 bZIP Inferred motif from similar protein – High-throughput in vitro WWACGTWD CREM ENSG00000095794 bZIP Known motif – High-throughput in vitro VVTBACGTVAB CRX ENSG00000105392 Homeodomain Known motif – High-throughput in vitro TAATCC CSRNP1 ENSG00000144655 Unknown Likely sequence specific TF according to literature or do