The Bank of Buffalo County, on Main St. in Gann Valley, South Dakota, is an Early Commercial-style building built in 1921. It was listed on the National Register of Historic Places in 1999.
It is a building with brick veneer walls, on a concrete foundation. It has a brick parapet and a shed roof. It and several similar buildings were built with brick after a severe fire on Main St. in 1921. It has also served as the Bank of Gann Valley and as the Gann Valley Post Office. With .
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