Matt O'Donnell may refer to:

Matt O'Donnell (journalist) (born 1972), American television journalist Matt O'Donnell (greyhound trainer) (1933–2016), Irish greyhound trainer Matt O'Donnell (Canadian football) (born 1989), Canadian football offensive lineman

See also Matthew O'Donnell (1932–1996), Irish priest and president of St. Patrick's College, Maynooth