Edward Payne may refer to:
Edward Payne (banker), governor of the Bank of England, 1771–1773 Edward John Payne (1844–1904), English barrister and historian Edward Howard Payne (1849–1908), businessman from Missouri; benefactor and namesake of Howard Payne University, Brownwood, Texas
See also Eddie Payne (1951–2021), American college basketball coach