Sayo may refer to:
Sayo (given name), a feminine Japanese given name Sayō, Hyōgo, a town in Sayō District, Hyōgo Prefecture, Japan Sayō District, Hyōgo, a district in Hyōgo Prefecture, Japan Sayo Station, a railway station in Hyōgo Prefecture, Japan Sayo (woreda), a woreda in the Oromia Region of Ethiopia
See also Siege of Saïo, a battle of the East African Campaign of World War II