Macclesfield is a market town in Cheshire, England.

Macclesfield may also refer to:

Macclesfield (UK Parliament constituency), a constituency represented in the British House of Commons Macclesfield (borough), a local government district and borough in Cheshire, England Macclesfield, South Australia, a town in the Adelaide Hills area of South Australia Macclesfield, Victoria, another town in Australia Macclesfield Bank or Zhongsha Islands is an elongated sunken atoll of underwater reefs and shoals in South China Sea and part of the disputed South China Sea Islands Macclesfield, North Carolina, a town in eastern North Carolina, U.S.A. William of Macclesfield, English cleric Macclesfield, a plantation in Isle of Wight County, Virginia that belonged to Josiah Parker

See also Macclesfield railway station (disambiguation) – any one of several vessels by that name Earl of Macclesfield Macclesfield Town F.C., an English football club in Cheshire