Wayne is an old English surname meaning a craftsman: wagon driver or builder.
Notable people with the surname "Wayne" include Anthony Wayne, general in the American colonial and United States armies Arthur Trezevant Wayne (1863–1930), American ornithologist Catie Wayne, Internet celebrity Charlie Wayne, UK musician David Wayne, American actor David Wayne (musician), American musician Don Wayne, American magic designer Don Wayne (songwriter), American country music songwriter Edward Johnson Wayne (1902–1990), British physician and professor of medicine Elsie Wayne, Canadian politician Fredd Wayne, American actor Gary Wayne, American baseball player Isaac Wayne (1772–1852), U.S. Congressman Isaac Wayne (1699–1774), Pennsylvania Provincial Assembly member, Captain in Pennsylvania Provincial Forces during the French and Indian War Jalen Wayne (born 1999), American football player James Moore Wayne, US congressman Jared Wayne (born 2000), Canadian American football player Jeff Wayne, American musician John Wayne, American actor Kenny "Blues Boss" Wayne (born 1944), American blues, boogie-woogie and jazz pianist, singer and songwriter Kyra Petrovskaya Wayne, Russian-American writer Leland Wayne, birth name of Metro Boomin, American record producer Naunton Wayne, British actor Olivia Wayne (born 1986), British sports journalist and television presenter Patrick Wayne, American actor Ralph Wayne (1932–2024), American politician Reggie Wayne, American football player Richard Wayne (died 1983), American murder victim Rick Wayne, St. Lucia media personality Ronald Wayne, American businessman William Wayne (1828–1901), American politician from Pennsylvania William Wayne (1855–1933), American politician from Pennsylvania
Fictional characters Bruce Wayne, the secret identity of Batman Thomas Wayne, the deceased father of Batman Martha Wayne, the deceased mother of Batman Damian Wayne, the son of Batman