Osborne House may refer to:
Australia Osborne House (Geelong), a historic building built in 1858, located in North Geelong, Victoria Osborne House, Millers Point, a heritage-listed house in Sydney, New South Wales
United Kingdom Osborne House, a former royal residence in East Cowes, Isle of Wight Osborne House, Cheadle, a former town hall in Staffordshire Osborne House School, a former school (c.1850–1940s) in Romsey, Hampshire
United States Edmund B. Osborne House, a historic residence located in Red Oak, Iowa Jessie Osborne House, near Jerome, Idaho, listed on the National Register of Historic Places in 1983 John Osborne House, a historic house at 909 King's Highway West in Fairfield, Connecticut Osborne House (Victor, New York), a historic home located at Victor in Ontario County, New York Prince Osborne House, a historic First Period house at 273 Maple Street in Danvers, Massachusetts
See also Osborn House, a historic house at 456 Rock Street in Fall River, Massachusetts Bowers–Livingston–Osborn House, a historic house in Parsippany, New Jersey