Cafferata is a surname. Notable people with the surname include:
Ana Maria Brescia Cafferata (born c. 1924), Peruvian billionaire heiress Francisco Cafferata (1861–1890), Argentine sculptor Gerónimo Cafferata Marazzi (1929–1986), Peruvian naval officer Hector A. Cafferata Jr. (1929–2016), American Marine and Medal of Honor recipient Juan Manuel Cafferata (1852–1920), Argentine politician Mario Brescia Cafferata (1929–2013), Peruvian billionaire businessman Patricia Dillon Cafferata (born 1940), American politician Pedro Brescia Cafferata (1921–2014), Peruvian businessman Raymond Cafferata (1897–1966), British Police Officer, see 1929 Hebron massacre Rosa Brescia Cafferata (born c. 1926), Peruvian billionaire heiress and philanthropist
See also Cafferatta, Santa Fe, town (comuna) in center-east Argentina