The Centre Cannot Hold may refer to:

"the centre cannot hold", a phrase from the poem "The Second Coming" by William Butler Yeats Literature American Empire: The Center Cannot Hold, a 2002 novel by Harry Turtledove The Centre Cannot Hold, a 2006 Star Trek novel by Mike W. Barr The Centre Cannot Hold, a 1990 novel by Brian Stableford The Center Cannot Hold: My Journey Through Madness, a 2007 book by Elyn Saks The Center Holds: Obama and His Enemies, a 2013 book by Jonathan Alter

Other uses Joan Didion: The Center Will Not Hold, a 2017 documentary directed by Griffin Dunne The Centre Cannot Hold, a 2004 EP by Digitonal The Centre Cannot Hold (album), a 2017 album by Ben Frost The Center Won't Hold, a 2019 album by Sleater-Kinney "The Center Will Not Hold, Twenty Centuries Of Stony Sleep", a 2021 song by Junkie XL from the soundtrack of Zack Snyder's Justice League