Comegys is a surname of Dutch origin. It was adopted in the United States by immigrants from the Netherlands, and is a portmanteau of the surnames Coman and Ghysen. Notable people with the surname include:

Celeste Comegys Peardon (1898–1988), American writer, educator Cornelius P. Comegys (1780–1851), American farmer and politician Dallas Comegys (born 1964), American basketball player Joseph P. Comegys (1813–1893), American judge, lawyer and politician Zelina Brunschwig (died 1981), American textile importer, born Zelina Comegys

See also Rick Comegy (born 1953), American football player and coach

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