Coco is a surname. Notable people with the surname include:

Alex Coco, American film producer Angela Coco, Australian sociologist Chester Coco (1915–2001), American politician and lawyer Ettore Coco (1908–1991), New York mobster Francesco Coco (born 1977), Italian retired football player Giuseppe Coco (1936–2012), Italian comics artist and illustrator Jack Coco (born 1998), American football player James Coco (1930–1987), American actor Juanita Coco (1975–1993), Australian singer and actress Menzy Coco (born 1989), Mauritian footballer Saúl Coco (born 1999), Equatoguinean footballer