William Wilkins may refer to:
William Wilkins (architect) (1778–1839), British architect and archaeologist William Wilkins (American politician) (1779–1865), American politician from Pennsylvania; served in both houses of Congress and as U.S. Secretary of War William Wilkins (educator) (1827–92), Australian teacher and co-founder of Fort Street High School William Glyde Wilkins (1854–1921), head of W.G. Wilkins Company, an architectural and engineering firm in Pittsburgh, Pennsylvania William Henry Wilkins (1860–1905), English writer William J. Wilkins (judge) (1897–1995), American lawyer and judge from the state of Washington William Wilkins (British politician) (1899–1987), British Labour Party MP for Bristol South, 1945–1970 Willie Wilkin (1916–1973), American football player William J. Wilkins (architect) (died 1932), American architect who worked in the Carolinas William Walter Wilkins (born 1942), former United States federal judge Billy Wilkins (active from 1991), Christian musician with the band Third Day