LCK may refer to:

Tyrosin-protein kinase Lck

Transport stations and areas Rickenbacker International Airport, Columbus, Ohio (IATA airport code LCK) Lockwood railway station, England (National Rail station code LCK) Lai Chi Kok station, Hong Kong (MTR station code LCK) Lim Chu Kang, Singapore

Gaming League of Legends Champions Korea, the top-level league for League of Legends competition in South Korea A shortened form of the word "Luck" used in many Role-playing games

Other Louis C.K., stand-up comedian, writer, producer, director, and actor Language Construction Kit, a feature of the website Zompist.com