Cazares is a surname originating in Spain. Notable people with the surname include:
Dino Cazares (born 1966), American musician Gabe Cazares (1920–2006), American mayor Gabriella Cázares-Kelly (born 1982), Tohono Oʼodham and American educator, community organizer, and politician Hugo Cázares (born 1978), Mexican boxer Juan Cazares (born 1992), Ecuadorian footballer