Sedghi is a surname. Notable people with the surname include:
Amir Hossein Sedghi (born 1996), Iranian footballer Arman Sedghi (born 1964), Iranian engineer and professor Hassan Sedghi, Iranian academic Kazem Sedghi, Iranian fighter pilot Hojjat Sedghi (born 1993), Iranian footballer Zubin Sedghi (born 16 September 1984) Persian-American neuroscientist, musical artist, and member of the Michigan band Tally Hall.