Nuzzi is an Italian surname. Notable people with the surname include:
Antonio Nuzzi (1926–2016), Italian Roman Catholic archbishop Ferdinando Nuzzi (1644–1717), Italian Roman Catholic cardinal Mariana Ximenes Nuzzi (born 1981), Brazilian actress
Mario Nuzzi (1603–1673), Italian painter Olivia Nuzzi (born 1993), American political journalist Paolo Nuzzi (born 1939), Italian film director and screenwriter