Bertolucci () is an Italian surname, originating from the given name Bertolo. Notable people with the surname include:
Attilio Bertolucci (1911–2000), Italian poet and writer Bernardo Bertolucci (1941–2018), Italian film director and screenwriter Davide Bertolucci (born 1988), Italian footballer Giuseppe Bertolucci (1947–2012), Italian film director and screenwriter Luana Bertolucci Paixão (born 1993), Brazilian footballer Paolo Bertolucci (born 1951), Italian tennis player Sergio Bertolucci (born 1950), Italian particle physicist
See also Bartolocci Bartolucci Bertolacci