Blackley is a toponymic surname that refers to the suburban area of Manchester. Notable people with the surname include:
Adam Blackley (born 1985), Australian baseball player Charles Harrison Blackley (1820–1900), English physician Jamie Blackley (born 1991), British actor Jim Blackley (1927–2017), Scottish-born Canadian jazz drummer John Blackley (born 1948), Scottish footballer and manager John Blackley (politician) (1862–1952), Australian politician Len Blackley (1915–1983), Australian rules footballer Seamus Blackley, American video game designer Travis Blackley (born 1982), Australian baseball player