Ayeni may refer to:
Adekunle Ayeni, Nigerian public relations practitioner, journalist, trained scientist and businessman Bosun Ayeni (born 1978), Nigerian footballer John Olatunde Ayeni (born 1967), Nigerian lawyer, investor and business magnate Kayode Ayeni (born 1987), American basketball player Phillip Ayeni (1949–2017), Navy Captain and first Administrator of Bayelsa State, Nigeria