Goldthwait is a surname of English origin. Notable people with the surname include:

Benjamin Goldthwait, British Army officer Bobcat Goldthwait (born 1962), American comedian, filmmaker, actor and voice actor Christopher E. Goldthwait (born 1949), American diplomat Ezekiel Goldthwait (1710–1782), Influential colonial Bostonian Jill Goldthwait, American politician

Places Goldthwait Sea, a sea formed after the last ice age that occupied roughly the area of the Gulf of Saint Lawrence Mount Goldthwait, a mountain of Ellsworth Land, Antarctica

See also Goldthwaite (surname) Goldman