Serpell is a surname. Notable people with the surname include:

Christopher Serpell (1910–1991), English journalist David Serpell (1911–2008), British civil servant who wrote the Serpell Report Grant Serpell (born 1944), English musician James Serpell (born 1952), American zoologist Namwali Serpell (born 1980), Zambian writer Robert Serpell (born 1944), British psychologist

See also Serpell Report