Hartenstein is a German surname. Notable people with the surname include:

Chuck Hartenstein (1942–2021), former relief pitcher in Major League Baseball Gustav Hartenstein (1808–1890), German philosopher and author Isaiah Hartenstein (born 1998), German-American basketball player Eddy Hartenstein, American CEO of Tribune Company and Los Angeles Times , German computer pioneer Werner Hartenstein (1908–1943), U-boat captain involved in the Laconia incident

See also Mike Hartenstine (born 1953), American football player