Requejo is a surname. Notable people with the surname include:
Jesús Requejo San Román (1880-1936), Spanish politician Jesús Tartilán Requejo (born 1940), Spanish footballer and coach Severino Requejo (born 1941), Spanish sport shooter Leuris Pupo Requejo (born 1977), Cuban shooter John Requejo (born 1996), American soccer player