Goodnight is a surname. Notable people with the surname include:
Charles Goodnight (1836–1929), 19th century American cattle baron Clarence J. Goodnight (1914–1987), American zoologist G. Thomas Goodnight, American argumentation and rhetorical scholar Isaac Goodnight (1849–1901), American politician from Kentucky James Goodnight, American businessman Owen Goodnight (1917–1967), American football player
Fictional characters Mary Goodnight, a character in James Bond novels and films