Stacpoole is a surname. Notable people with the surname include:
Frederick Stacpoole (1813–1907), English engraver Henry De Vere Stacpoole (1863–1951), Irish author Richard Fitzgeorge de Stacpoole, 1st Duke de Stacpoole (1787–1848), Anglo-French Catholic aristocrat William Stacpoole (1830–1879), Irish nationalist politician