59th Regiment or 59th Infantry Regiment may refer to:

59th Regiment of Foot (disambiguation), three British Army units carried this name 59th (Warwickshire) Searchlight Regiment, Royal Artillery, a unit of the British Army 59th Scinde Rifles (Frontier Force), a unit of the British Indian Army 59 Medium Regiment (India), a unit of the Indian Army 59th Infantry Regiment (United States), a unit of the United States Army 59th Air Defense Artillery Regiment, a unit of the United States Army

American Civil War Union (Northern) Army 59th Illinois Volunteer Infantry Regiment 59th Indiana Infantry Regiment 59th New York Volunteer Infantry Regiment 59th Ohio Infantry

Confederate (Southern) Army 59th Virginia Infantry