The canton of Sillé-le-Guillaume is an administrative division of the Sarthe department, northwestern France. Its borders were modified at the French canton reorganisation which came into effect in March 2015. Its seat is in Sillé-le-Guillaume.

It consists of the following communes:

Ancinnes Assé-le-Boisne Assé-le-Riboul Beaumont-sur-Sarthe Bérus Béthon Bourg-le-Roi Chérancé Chérisay Crissé Doucelles Douillet Fresnay-sur-Sarthe Fyé Gesnes-le-Gandelin Grandchamp Le Grez Juillé Livet-en-Saosnois Maresché Moitron-sur-Sarthe Montreuil-le-Chétif Mont-Saint-Jean Moulins-le-Carbonnel Neuvillette-en-Charnie Oisseau-le-Petit Parennes Pezé-le-Robert Piacé Rouessé-Fontaine Rouessé-Vassé Rouez Saint-Aubin-de-Locquenay Saint-Christophe-du-Jambet Saint-Georges-le-Gaultier Saint-Léonard-des-Bois Saint-Marceau Saint-Ouen-de-Mimbré Saint-Paul-le-Gaultier Saint-Rémy-de-Sillé Saint-Victeur Ségrie Sillé-le-Guillaume Sougé-le-Ganelon Thoiré-sous-Contensor Le Tronchet Vernie Vivoin

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