Give Up the Ghost may refer to:

Give Up the Ghost (band), now American Nightmare, a hardcore punk band Give Up the Ghost (album), by Brandi Carlile, 2009 "Give Up the Ghost", a song by Ariana and the Rose "Give Up the Ghost", a song by C2C from Tetra "Give Up the Ghost", a song by Immature from The Journey "Give Up the Ghost", a song by Radiohead from The King of Limbs "Give Up the Ghost", a song by Starsailor from Good Souls: The Greatest Hits "Give Up the Ghost", a song by Switches from Heart Tuned to D.E.A.D. , a 2019 Jordanian short film directed by Zain Duraie

See also Giving Up the Ghost (disambiguation)