Hirono may refer to:
People Hirono (surname), a Japanese surname Mazie Hirono, current Democratic US Senator from the state of Hawaii.
Places Hirono, Fukushima, Japan Hirono, Iwate, Japan Hirono Station (Fukushima), a stop on the West Japan Railway's Fukuchiyama Line Hirono Station (Hyogo), a stop on the Kobe Electric Railway's Sanda Line Hirono Power Station, a fossil-fuel power station operated by Tepco