The canton of Le Sud-Est agenais is an administrative division of the Lot-et-Garonne department, southwestern France. It was created at the French canton reorganisation which came into effect in March 2015. Its seat is in Layrac.
It consists of the following communes:
Astaffort Castelculier Caudecoste Clermont-Soubiran Cuq Fals Grayssas Lafox Layrac Puymirol Saint-Caprais-de-Lerm Saint-Jean-de-Thurac Saint-Nicolas-de-la-Balerme Saint-Pierre-de-Clairac Saint-Romain-le-Noble Saint-Sixte Saint-Urcisse Sauvagnas Sauveterre-Saint-Denis
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