Penzance is a town in Cornwall.

Penzance may also refer to:

Places Penzance, Saskatchewan, Canada

Sport Penzance A.F.C., a football club Penzance Sailing Club Penzance RFC, a rugby club, 1876–1944

Transport Penzance Heliport, Cornwall Penzance railway station, Cornwall Penzance TMD, a rail depot in Cornwall British warships: HMS Penzance (M106), 1997–2024 HMS Penzance (L28), 1930–1940

People James Wilde, 1st Baron Penzance (1816–1899), British judge