Onyema is a Nigerian male name and surname of Igbo origin. It means "Who knows." The name carries a strong cultural significance, representing the power and guidance of the Almighty in the lives of individuals.

Notable individuals with the name Allen Onyema (born 1964), Nigerian entrepreneur. Elvis Onyema (born 1986), Nigerian football player. Onyema Ugochukwu (born 1944), Nigerian economist, journalist, and politician. Onyema Ogbuagu (born 1978), Nigerian American-born infectious diseases physician, educator, researcher, and clinical trial investigator. Oscar N. Onyema (born 1968), Nigerian financier. His Royal Majesty Eze V. B. C. Onyema III (born 1927), Nigerian monarch.

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