In music, Op. 49 stands for Opus number 49. Compositions that are assigned this number include:

Beethoven – Piano Sonatas Nos. 19 and 20 Brahms – Wiegenlied Chopin – Fantaisie in F minor Elgar – The Apostles Klebe – Jacobowsky und der Oberst Krenek – Der Diktator Mendelssohn – Piano Trio No. 1 Milhaud – Little Symphony No. 2 Schumann – Romanzen & Balladen volume II (3 songs) Scriabin – Prelude in F major, Op. 49, No. 2 Shostakovich – String Quartet No. 1 Sibelius – Pohjola's Daughter (), tone poem for orchestra (1906) Tchaikovsky – 1812 Overture