Portales may refer to:
People Amanda Portales (born 1961), Peruvian artist Diego Portales (1793–1837), Chilean politician Javier Portales (1937–2003), Argentine actor Juan Antonio Portales (born 1996), Mexican footballer Suceso Portales (1904–1999), Spanish activist
Places Portales, New Mexico, a city in the United States Portales Forest Reserve, in New Mexico
Other uses Diego Portales University, a Chilean University Portales metro station, in Mexico City Portales Municipal Airport, an airport of the United States