Kofo is a Nigerian given name. Notable people with the name include:
Kofo Abayomi (1896–1979), Nigerian ophthalmologist and politician Kofo Akinkugbe, Nigerian technology entrepreneur Kofoworola "Kofo" Omogoriola Olanipekun, a fictional character on the U.S. TV series Bob Hearts Abishola
See also KOFO, a radio station from Ottawa, Kansas, United States