Marcuzzi is an Italian surname. Notable people with the surname include:
Alessia Marcuzzi (born 1972), Italian television personality and actress Angelo Marcuzzi (died 1453), Roman Catholic prelate, Bishop of Telese Michael Marcuzzi, American visual effects artist Santé Marcuzzi (1934–2020), French rower Sebastiano Marcuzzi (1725-1790) Italian abbot from Friuli and writer of texts on religion