Estriol 3-glucuronide, or oestriol 3-glucuronide, also known as estriol 3-β-D-glucosiduronic acid, is a natural, steroidal estrogen and a glucuronic acid (β-D-glucopyranuronic acid) conjugate of estriol. It is found in the urine of women as a reversibly formed metabolite of estriol. The positional isomer of estriol 3-glucuronide, estriol 16α-glucuronide, also occurs as an endogenous metabolite of estriol, but to a much greater extent in comparison.
Formation A glucuronosyltransferase anzyme converts estriol to its glucuronide by adding a sugar acid at the phenolic hydroxy group, with uridine diphosphate (UDP) as byproduct:
See also Estrogen conjugate Estradiol glucuronide Estrone glucuronide Estradiol sulfate Estrone sulfate Lipoidal estradiol Catechol estrogen
References
External links Metabocard for Estradiol 3-Glucuronide – Human Metabolome Database