Andrew James Santino (born October 16, 1983) is an American stand-up comedian and actor. He is known for television series and films such as Sin City Saints, The Disaster Artist, Mixology, I'm Dying Up Here, Beef, and Dave. He was also the star of a YouTube web series called Duncan Rocks.
Early life and education Santino grew up in the River North neighborhood of Chicago, and he is of half Italian and half Irish descent. Raised by a single mother, he graduated from Naperville North High School in 2002, and then attended Arizona State University.
Career On I'm Dying Up Here, Santino played Bill Hobbs, a talented, popular comedian who sabotages himself with a bitter attitude and negative outlook on life. From 2020 to 2023, Santino starred in the series Dave, which tells the fictionalized story of rapper Lil Dicky; Santino portrayed his roommate and manager. In 2017, he released a Showtime special called Home Field Advantage. He played a recurring character in the NBC drama This Is Us, as a producer of the fictional sitcom The Manny.
Santino produces and hosts the podcast Whiskey Ginger, where he interviews friends in the entertainment industry as they reflect on their past while sipping whiskey. In 2020, Santino began co-hosting the Bad Friends podcast with Bobby Lee.
Santino hosts golf content on a YouTube series called No Bad Lies. In August 2025, Santino participated in the inaugural Internet Invitational organized by Barstool Sports and Bob Does Sports.
In 2025, Santino participated in the Riyadh Comedy Festival. Joey Shea, Saudi Arabia researcher at Human Rights Watch, said in a statement that the Saudi government is using the comedy festival to whitewash its human rights abuses.
In 2026, Santino partnered with comedian Bobby Lee on a 10-episode, unscripted comedy series, The Bad Game Show, produced by All Things Comedy. The game show will involve celebrities completing crazy and chaotic challenges in Bobby Lee's mom's basement.
Filmography Film YearTitleRoleNotes2008Henry Poole Is HereHospital Orderly2010Santa's Xmas PartyAndrewShort film; also writer and executive producer2012Funny GirlHimselfShort film2013Dance CrewDef Leo PardShort film2014WarrenRob Brown2016DeanChadSXSW Comedy with Natasha LeggeroHimself2017Show BusinessDoctorShort filmThe Disaster ArtistScott Holmes / 'Mike'2018Little BitchesTrentGame Over, Man!Officer Hank2020FriendsgivingRick2022Me TimeAlan Geller2023House PartyPeterFool's ParadiseComedian ScrambledJesse Robinson 2024Ricky Stanicky JT 2025 Happy Gilmore 2 Himself Cameo Now You See Me: Now You Don't Brett Finnegan2026 Goat ChuckTBA Me Time 2 TBA Filming
Stand-up specials YearTitlePlatform2018Home Field AdvantageAmazon Prime2023CheeseburgerNetflix2025White NoiseHulu
Television YearTitleRoleNotes2009–10CraftyEli / Craft ServiceSeries regular (8 episodes)2010Big on the WebHimself (host)Unknown episode(s)The Surf ReportHimself (host)Unknown episode(s)2012Punk'dField AgentRecurring role (12 episodes)Segment producer (5 episodes)The OfficeShip Sales Transport CaptainEpisode: "The Boat"2013Arrested DevelopmentEmployerEpisode: "The B. Team"Family TreeConfederate SoldierEpisode: "Civil War"Children's HospitalJasper 'Pants'Episode: "Imaginary Friends"Adam Devine's House PartyHimselfEpisode: "Ex-Girlfriend"Who Gets the Last Laugh?Field producerEpisode: "Kunal Nayyar / Bill Bellamy / Jeff Dye"2014DeadbeatSports CommentatorEpisode: "The Hot God Contest"MixologyBruceSeries regular (13 episodes)The LeagueShappsEpisode: "EBDBBnB"How I Met Your DadDannyUnaired CBS/FOX pilotLast Call with Carson DalyHimself (guest)Episode: "J.B. / Andrew Santino / Warm Soda"2015Sin City SaintsJake TuliusSeries regular (8 episodes)The Sixth LeadTow Truck OperatorEpisode: "Trouble at the Security Gate"ConanHimself (comic guest)Episode: "Edward Norton / Melissa Rauch / Andrew Santino"Roast of Justin Bieber Pre-ShowHimself (host)TV specialThe Meltdown with Jonah and KumailHimself (guest)Episode: "The One with All the Spitting"The Half HourHimself (comedian)Episode: "Must CC: The Half Hour"2016American Dad!Jaramillo Henchman (voice role)Episode: "Fight and Flight"2016–17Here's the RubNikola PopovSeries regular, executive producer (12 episodes)2016–22This Is UsCasey3 episodes2017The Late Late Show with James CordenHimself (guest)Episode: "Jim Carrey / Al Madrigal / Andrew Santino / Erik Griffin"2017–18I'm Dying Up HereBilly HobbsSeries regular (20 episodes)2018Alone TogetherKyleEpisode: "Nurse Esther"2019FamSpenceEpisode: "Party Girl"2019–20Lights Out with David SpadeHimself (panelist)3 episodes2020Curb Your EnthusiasmPlumberEpisode: "Insufficient Praise"2020–23DaveMikeSeries regular (30 episodes)2021–23Ten Year Old TomVarious voices5 episodes2021FairfaxBiff (voice)Episode: "Dale Hates His Dad"2023–presentRoyal CrackersTheodore "Theo" Hornsby Jr. (voice)Main role2023BeefMichaelRecurring role2024Dinner Time Live with David ChangHimself (guest)Episode: "Choose Your Own Adventure Volume 2"2025Last MealsHimself (guest)Episode: "Andrew Santino Eats His Last Meal"
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