PTB may refer to:

Government and politics Bermuda Public Transportation Board Bessarabian Peasants' Party (), a political party in the Kingdom of Romania Brazilian Labour Party (1945) (), dismantled after the 1964 military-led coup d'état Brazilian Labour Party (1981) (), merged with Patriota to form the new Democratic Renewal Party in 2022. Pakistan Tobacco Board Party of Labour of Burkina (), a political party in Burkina Faso Physikalisch-Technische Bundesanstalt, the national metrology institute of Germany Workers' Party of Belgium (), a Belgian political party

Science and medicine N-Phenacylthiazolium bromide, a cross-link breaker Permian-Triassic boundary, a mass extinction event Phosphotyrosine-binding domain (PTB-domain), a protein domain Polypyrimidine tract-binding protein, an RNA-binding protein Pulmonary tuberculosis, manifestation of tuberculosis in the lungs

Technology Project team builder, a project management simulator Public Test Build, in software testing Push to break, electronics push switch Packet Too Big, an ICMPv6 message; see IPv6 packet Pounds of salt per thousand barrels of crude oil; see Desalter .ptb, a file extension used by musical tablature authoring tool Power Tab Editor

Transport Pentre-bach railway station, in Wales Petit train de banlieue, a passenger train in Senegal Petersburg station, an Amtrak station serving Petersburg, Virginia Voepass Linhas Aéreas, a Brazilian airline

Other uses P.T.B (album), by rapcore group Kingspade Placer Theatre Ballet, an American ballet company Portland Trail Blazers, an American professional basketball team Proto-Tibeto-Burman language Proto-Torres-Banks language, a reconstructed language from Vanuatu

See also PTP (disambiguation) The powers that be (disambiguation)