Sempill or Semple may refer to:
People Francis Sempill (1616?–1682), Scottish writer, son of Robert the younger James Sempill (1566–1626), Scottish courtier and diplomat Hugh Sempill (1596–1654), Scottish mathematician Robert Sempill (c.1530–1595), Scottish balladeer Robert Sempill the younger (1595?–1663?), Scottish writer, son of Robert William Forbes-Sempill, 19th Lord Sempill (1893–1965), Scottish pioneering aviator and Japanese spy
Other uses Clan Sempill, a Lowland Scottish clan Lord Sempill, a title in the Peerage of Scotland Sempill Mission, a 1921 military mission to Japan