PD-137889 (N-methylhexahydrofluorenamine) is a chemical compound that is active as an NMDA receptor antagonist in the central nervous system at roughly 30 times the potency of the "flagship" of its class, ketamine, and substitutes for phencyclidine in animal studies. Ki [3H]TCP binding = 27 nM versus ketamine's Ki = 860 nM.Polycyclic amine derivatives useful as cerebrovascular agents United States Patent; Coughenour, et al. Family ID: 22686445 Appl. #07/186,834
See also Aptiganel Dizocilpine Fourphit Metaphit Selfotel
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