Mthembu may refer to: Gideon Mthembu (born 1963), Swazi sports official and retired runner Jackson Mthembu (1957–2021), South African politician Precious Mthembu (born 1984), South African netball player Ricardo Mthembu (1970–2020), South African politician Russel Mthembu (born 1947), South African singer Siphelele Mthembu (born 1987), South African footballer Thabani Mthembu (born 1994), South African footballer

See also Mthembu v Letsela, important case in South African customary law, 1996