Megginson is a surname. Notable people with the name include:

Kate Megginson (born 2003), Canadian Actress David Megginson (born 1964), Canadian computer consultant Leon C. Megginson (born 1921), American business academic Mitchel Megginson (born 1992), Scottish footballer Robert Megginson (born 1948), American mathematician

See also Ernest Megginson House, historic home in Alabama