The surname Gessen is a transliteration of the Russian spelling "Гессен" of the surname of Russified persons coming from the House of Hesse, including the last ruling Russian Empress Alix of Hesse: , .
The surname may refer to:
Boris Hessen (1893–1936), Soviet physicist, philosopher, and historian of science, whose surname is sometimes transliterated as Gessen (1866–1943), Russian lawyer, statesman, and essayist Keith Gessen (born 1975), Russian-born American novelist, journalist, and editor Masha Gessen (born 1967), Russian and American journalist, author, translator, and activist (1887–1950), Russian philosopher, educator and publisher Vladimir Gessen (disambiguation), which may refer to: Vladimir Augusto Gessen Rodríguez, Venezuelan politician, journalist and psychologist Vladimir Matveevich Gessen (1868–1920), Russian jurist and politician
See also Hessen (disambiguation)