Manusela may refer to:
Animal Manusela mosaic-tailed rat, a species of rodent that is found in Indonesia Chloroclystis manusela, a species of moth that is found in Indonesia
Anthropology Manusela people, an idigineous people from Seram island, Indonesia Manusela language, spoken by Manusela people
Place Manusela National Park, located in Seram island, Indonesia