Charles Isaac and Lizzie Hunter Moore Anderson House is a historic home located at Commerce, Scott County, Missouri. It was built in 1902, and is a -story, Free Classic Queen Anne style frame dwelling measuring 61 feet by 41 feet. It has a hipped roof with prominent front gable and dormers. It features a wrap-around porch with nine Doric order columns. Also on the property are the contributing garage (1905) and tool shed. (includes 5 photographs from 2006)

It was added to the National Register of Historic Places in 2006.

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