The men's singles of the 2008 ECM Prague Open tournament was played on clay in Prague, Czech Republic.
Dušan Lojda was the defending champion, but lost in first round to Augustin Gensse.
Jan Hernych won the title by defeating Lukáš Dlouhý 4–6, 6–2, 6–4 in the final.
Seeds
Draw
Finals
Top half
Bottom half
External links Main Draw Qualifying Draw