Burkholder-O'Keefe House is a historic home located at Moberly, Randolph County, Missouri. It was built in 1872, and is a two-story, Italianate style frame I-house. It features a two-story front porch with gable roof. It is one of the oldest surviving houses in Moberly. (includes 22 photographs from 1989)
It was listed on the National Register of Historic Places in 1989.
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