2,5-Dimethoxy-p-cymene, or thymohydroquinone dimethyl ether, is a phytochemical found in the essential oils of plants within the family Asteraceae. These essential oils, which contain the compound as a major component of the oil, have antifungal, antibacterial, and insecticidal properties.
Natural occurrence 2,5-Dimethoxy-p-cymene occurs in a variety of different plants' essential oils. Examples include:
Ayapana triplinervis (92.8%) Apium leptophyllum (50.7 to 80.24%) Cyathocline purpurea (57.4%) Arnica montana (32.6%) Laggera crispata (32.2%) Blumea perrottetiana (30.0%) Eupatorium capillifolium (20.8%) Sphaeranthus indicus (18.2%) Limbarda crithmoides (16.4) Bubonium imbricatum (16.2%)
Chemical synthesis 2,5-Dimethoxy-p-cymene can be synthesized from carvacrol by aromatic halogenation followed by nucleophilic substitution with sodium methoxide and Williamson ether synthesis using methyl iodide.
See also Thymoquinone
References